Dr.Jayamurthy P

Dr.Jayamurthy P
  • Dr.Jayamurthy P
  • Principal Scientist
  • 0471-2515347

http://niist.irins.org/profile/64963

Academic Qualification

 

  • 2009 – Ph.D from Defence Institute of Physiology and Allied Sciences (DRDO), Delhi (Bharathiyar University, Coimbatore)
  • M. Sc. (Bharathidasan University)
  • B. Sc. (University of Madras)

 

Award1

 

Kerala State Young Scientist Award
Kerala State Council for Science,Technology & Environment-KSCSTE (2016)
Award2

 

Best paper award
at National conference on emerging avenues in Food technology for better health and safety held at Kollam (2013)
Award3

 

Best paper award
at 5th International Conference on Advances in Food Technology and Health Sciences(ICFTHS-2014) JNU, Delhi
Award4

 

 Best poster award
at International symposium on Phytochemicals,Trivandrum (2015)
Award5

 

 Best Poster award
at International conference on advances in degenerative diseases and molecular interventions (ADDMI-2017)

 

thesis1

 

Dhanya R
Mechanistic role of citrus flavonoids and their glycoconjugates in the management of type 2 diabetes (2016), CUSAT
thesis2

 

Syama HP
Phytochemical investigation ofSyzygium cumini seeds and its impact in ameliorating life style associated diseases (2017), CUSAT

 

 

im1

 

 Ms. Anusha C V
Junior Research Fellow
Email ID: anuchandrancv1[at]gmail.com
im2

 

 Ms. Syama H P
Junior Research Fellow
Email ID: hp_sym[at]yahoo.com
im3

 

 Ms. Dhanya R
Junior Research Fellow
Email ID: dhanya_tintu[at]yahoo.co.in
im4

 

 Mrs. Jyothi C L
Project Assistant
Email ID: jyothick[at]gmail.com

 

Research Supervision

 

  • Postdoctoral researcher (Past/current): 2
  • Ph. D. Awarded: 2
  • Ph. D. Ongoing : 3
  • Project Assistants (Past/Current): 8
  • M. Sc. Students: 10

Publications

Selected peer-reviewed publications

 

  • Prabha B, Neethu S, Krishnan SL, Sherin DR, Madhukrishnan M, Ananthakrishnan R, Rameshkumar KB, Manojkumar TK, Jayamurthy P, Radhakrishnan KV. Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair. Bioorg Med Chem.2018 Jul 23;26(12):3461-3467. doi: 10.1016/j.bmc.2018.05.020
  • Syama H.P., T. Sithara, S. Lekshmy Krishnan, P. Jayamurthy. Syzygium cumini seed attenuates LPS induced inflammatory response in murine macrophage cell line RAW264.7 through NF-?B translocation. Journal of Functional Foods 44 (2018) 218–226
  • Syama H P, K B Arun, George Sl, R Dhanya, S S Anusree, P. Nisha, L R Shankar, A Sundaresan, P Jayamurthy. Syzygium cumini seed exhibits antidiabetic potential via multiple pathways involving inhibition of ??glucosidase, DPP?IV, glycation, and ameliorating glucose uptake in L6 cell lines. Journal of food processing and preservation, (2018), 42 (2) DOI: 10.1111/jfpp.13464
  • Jamsheena V, R K. Mishra, K S. Veena, S Sini, P Jayamurthy, and Ravi S. L. New 1,2-Dihydropyridine-Based Fluorophores and Their Applications as Fluorescent Probes. ACS Omega, (2018), 3 (1), pp 856–862. DOI: 10.1021/acsomega.7b01835
  • Dhanya R, Arya Das, Nisha P And Jayamurthy P. Quercetin, a lead compound against type 2 diabetes ameliorates glucose uptake via AMPK pathway in skeletal muscle cell line. Front. Pharmacol. 2017, doi: 10.3389/fphar.2017.00336
  • Syama H. P. , Arya A. D. , Dhanya R. , Nisha P. , Sundaresan A. , Jacob E. , Jayamurthy P. . Quantification of phenolics in Syzygium cumini seed and their modulatory role on tertiary butyl-hydrogen peroxide-induced oxidative stress in H9c2 cell lines and key enzymes in cardioprotection. Journal of Food Science and Technology. J Food Sci Technol, 2017, doi:10.1007/s13197-017-2651-3
  • Jubi J, Reshma UR, Syama H P, Jayamurthy P, Dileep Kumar B S. Enhanced antibacterial metabolite production through the application of statistical methodologies by a Streptomyces nogalater NIIST A30 isolated from Western Ghats forest Soil. PLoS One. Public Library of Science; 2017; 4
  • Syama Hari Priya, Nisha Prakasan, and Jayamurthy Purushothaman. Antioxidant activity, phenolic-flavonoid content and high-performance liquid chromatography profiling of three different variants of Syzygium cumini seeds: A comparative study. J Intercult Ethnopharmacol. 2017 Jan-Mar; 6(1): 107–114. doi: 10.5455/jice.20161229055555
  • Arun K. B., P. Jayamurthy, C. V. Anusha, S. K. Mahesh and P. Nisha. Studies on activity guided fractionation of pomegranate peel extracts and its effect on antidiabetic and cardiovascular protection properties. Journal ofFoodProcessing andPreservation; 2016;Doi:10.1111/Jfpp.13108
  • Anees P, Karivachery V. Sudheesh, P Jayamurthy, Arunkumar R. C, R V. Omkumar and A Ajayaghosh. A protein–dye hybrid system as a narrow range tunable intracellular pH sensor. Chemical Science; 2016; DOI: 10.1039/C6SC02659A
  • Arun KB, Chandran J, Dhanya R, Krishna P, Jayamurthy P, Nisha P. A comparative evaluation of antioxidant and antidiabetic potential of peel from young and matured potato. Food Biosci. Elsevier; 2015;9: 36–46.
  • Arun KB, Persia F, Aswathy PS, Chandran J, Sajeev MS, Jayamurthy P, et al. Plantain peel-a potential source of antioxidant dietary fibre for developing functional cookies. J Food Sci Technol. Springer India; 2015; 1–10.
  • Dhanya R, Arun KB, Nisha VM, Syama HP, Nisha P, Kumar TRS, et al. Preconditioning L6 Muscle Cells with Naringin Ameliorates Oxidative Stress and Increases Glucose Uptake. PLoS One. Public Library of Science; 2015;10.
  • Dhanya R, Arun KB, Syama HP, Nisha P, Sundaresan A, Santhosh Kumar TR, et al. Rutin and quercetin enhance glucose uptake in L6 myotubes under oxidative stress induced by tertiary butyl hydrogen peroxide. Food Chem. Elsevier; 2014;158: 546–554.
  • Janu C, Kumar DR, Reshma M V, Jayamurthy P, Sundaresan A, Nisha P. Comparative Study on the Total Phenolic Content and Radical Scavenging Activity of Common Edible Vegetable Oils. J Food Biochem. Wiley Online Library; 2014;38: 38–49.
  • Jayamurthy P, Aparna B, Gayathri G, Nisha P. Evaluation of antioxidant potential of inflorescence and stalk of plantain (Musa Sapientum). J Food Biochem. Wiley Online Library; 2013;37: 2–7.
  • Janu C, Padmakumari Amma KP, Nirmala Menon A, Jayamurthy P, Nisha P. Effect of enzyme assisted extraction on quality and yield of volatile oil from black pepper and cardamom. Springer; 2012;
  • Reshma M V, Kiran CR, Nisha P, SobanKumar DR, Sundaresan A, Jayamurthy P. Trans fat content in labeled and unlabelled Indian bakery products including fried snacks. Int Food Res J. 2012;19.
  • Sreejith S, Divya KP, Jayamurthy P, Mathew J, Anupama VN, Philips DS, et al. Heteroaromatic donors in donor–acceptor–donor based fluorophores facilitate zinc ion sensing and cell imaging. Photochem Photobiol Sci. RSC; 2012;11: 1715–1723.
  • Sasidharan I, Sundaresan A, Nisha VM, Kirishna MS, Raghu KG, Jayamurthy P. Inhibitory effect of Terminalia chebula fruit extracts on digestive enzyme related to diabetes and oxidative stress. J Enzyme Inhib Med Chem.; 2012;27: 578–586.
  • Shukla D, Saxena S, Purushothaman J, Shrivastava K, Singh M, Shukla S, et al. Hypoxic preconditioning with cobalt ameliorates hypobaric hypoxia induced pulmonary edema in rat. Eur J Pharmacol. Elsevier; 2011;656: 101–109.
  • Jayamurthy P, Suryakumar G, Shukla D, Jayamurthy H, Kasiganesan H, Kumar R, et al. Modulation of hypoxia-induced pulmonary vascular leakage in rats by seabuckthorn (Hippophae rhamnoides L.). Evidence-Based Complement Altern Med. Hindawi Publishing Corporation; 2011;2011.
  • Divya KP, Sreejith S, Balakrishna B, Jayamurthy P, Anees P, Ajayaghosh A. A Zn2+-specific fluorescent molecular probe for the selective detection of endogenous cyanide in biorelevant samples. Chem Commun. Royal Society of Chemistry; 2010;46: 6069–6071.
  • Sreejith S, Jayamurthy P, Aneesa P, Ajayaghosh A. A Zn 2-specific fluorescent molecular probe for the selective detection of endogenous cyanide in biorelevant samples. Chem Commun. 2010;46: 6069–6071.
  • Shukla D, Saxena S, Jayamurthy P, Sairam M, Singh M, Jain SK, et al. Hypoxic preconditioning with cobalt attenuates hypobaric hypoxia-induced oxidative damage in rat lungs. High Alt Med Biol. Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801-5215 USA; 2009;10: 57–69.
  • Geetha S, Basu M, Jayamurthy AS, Malhotra AS, Pal K, Prasad R, et al. Protective and therapeutic potentials of seabuckthorn (Hippophae rhamnoides). Seabuckthorn (Hippophae L) a Multipurp wonder plant. Daya Books; 2008;3: 245.
  • Geetha S, Jayamurthy P, Pal K, Pandey S, Kumar R, Sawhney RC. Hepatoprotective effects of sea buckthorn (Hippophae rhamnoides) against carbon tetrachloride induced liver injury in rats. J Sci Food Agric. Wiley Online Library; 2008;88: 1592–1597.
  • Nisha P, Abdul Nazar P, Jayamurthy P. A comparative study on antioxidant activities of different varieties of Solanum melongena. Food Chem Toxicol. Elsevier; 2009;47: 2640–2644.
  • Jayamurthy P, Suryakumar G, Shukla D, Malhotra AS, Kasiganesan H, Kumar R, et al. Modulatory effects of seabuckthorn (Hippophae rhamnoides L.) in hypobaric hypoxia induced cerebral vascular injury. Brain Res Bull. Elsevier; 2008;77: 246–252.
  • Basu M, Prasad R, Jayamurthy P, Pal K, Arumughan C, Sawhney RC. Anti-atherogenic effects of seabuckthorn ( Hippophaea rhamnoides) seed oil. Phytomedicine. Elsevier; 2007;14: 770–777.
  • Geetha S, Basu M, Jayamurthy P, Malhotra AS, Pal K, Prasad R, Kumar R, Sawhney RC. (2008). Chapter 24 – Protective and therapeutic potentials of Seabuckthorn (Hippophae rhamnoides L.). Seabuckthorn: A Multipurpose Wonder Plant, Vol. III- Advances in Research and Development/Virendra Singh. Delhi, Daya Publishing House, pp-566.
  • Geetha S, Jayamurthy P, Pal K, Shweta P, Ratan K, Sawhney RC. (2008). Hepatoprotective effects of seabuckthorn (Hippophae rhamnoides L.) against carbon tetrachloride induced liver injury in rats. J Sci Food Agric 88:1592–1597.
  • Jayamurthy P, Geetha S, Dhananjay S, Malhotra SA, Harinath K, Ratan K, Sawhney RC, Arumughan C. (2008). Modulatory effects of seabuckthorn (Hippophae rhamnoides L.) in hypobaric hypoxia induced cerebral vascular injury. Br Res Bull 77:246–252.
  • Jayamurthy P, Geetha S, Dhananjay S, Himani J, Harinath K, Rajesh K, Sawhney RC. (2009). Modulation of hypoxia-induced pulmonary vascular leakage in rats by seabuckthorn (Hippophae rhamnoides L.). eCAM (Published online on December– doi:10.1093/ecam/nep199).
  • Nisha P, Abdul Nazar P, Jayamurthy P. (2009). A comparative study on antioxidant activities of different varieties of Solanum melongena. Food Chem Toxicol. 47, 2640-2644.
  • Shishir Tandon, Jayamurthy P and Sawhney RC. (2009). Study of fatty acids profile in leaves of seabuckthorn collected from Leh Region. International Seabuckthorn Research and Development. 41-43.
  • Shukla D, Saxena S, Jayamurthy P, Sairam M, Singh M, Jain SK, Bansal A, Ilavazaghan G. (2009). Hypoxic preconditioning with cobalt attenuates hypobaric hypoxia-induced oxidative damage in rat lungs. High Alt Med Biol 10:57-69.
  • Kizhumuri P.D, Sivaramapanicker Sreejith, Bugga Balakrishna, Purushothaman Jayamurthy, Palappuravan Anees, Ayyappanpillai Ajayaghosh. (2010). A Zn2+-specific fluorescent molecular probe for the selective detection of endogenous cyanide in biorelevant samples. Chem. Commun. 46, 6069 – 6071.

 

Broad areas of Interest

 

  • Biochemistry
  • Immunology
  • Immunology
  • Molecular biology
  • Cell biology