Dr.Jubi John

Dr.Jubi John
  • Dr.Jubi John
  • Senior Scientist
  • 0471-2515319

Google scholar: https://scholar.google.co.in/citations?user=yeGoVEYAAAAJ&hl=en

Dr. Jubi John received his Bachelor’s degree in Chemistry (Christian College, Chengannur) in 2002 and Master’s degree (St. Berchmans College, Changanacherry) in 2004. He completed his Ph. D. in Chemistry from University of Kerala in March 2010 based on the work done in the area of ‘Palladium catalyzed transformation of azabicyclic olefins’ under the guidance of Dr. K. V. Radhakrishnan at CSIR–NIIST, Thiruvananthapuram. Soon after he was awarded the CEA-Eurotalents Fellowship and moved to Centre for Atomic Energy (CEA-Saclay) in France and worked in the group of Dr. Eric Doris (May 2010 – May 2011). Later he was awarded the prestigious Alexander von Humboldt fellowship to work (August 2011 – January 2013) in the group of Prof. Henning Hopf at the Institute of Organic Chemistry, TU Braunschweig, Germany. In February 2013, he moved to Katholieke Universiteit Leuven and worked with Prof. Wim Dehaen and Prof. Jan Balzarini and stayed there until February 2015. In 2014, Dr. John was awarded the DST-Young scientist start up grant and in July 2015, he joined CSIR-NIIST and continued in the position for seven months. In March 2016, he joined as a Scientist fellow (Quick hire scheme) and remained in the position until March 2019. Dr. John was appointed as a senior scientist in December 2019 at the Chemical Sciences and Technology Division of CSIR–NIIST. In 2017 and early 2019, he was awarded experienced researcher visits to Germany by the Alexander von Humboldt foundation. His current research interests include development of novel antiviral drug candidates, novel fused heterocyclic motifs, organo-and transition metal catalyzed reactions, heterogeneous catalysis and development of dyes for DSC applications.

  1. December 2019 to date: Senior Scientist at Organic Chemistry Section, CSIR-NIIST, Thiruvananthapuram, India.
    The responsibilities at CSIR-NIIST include scientific research, mentoring of Doctoral and Masters’ students and teaching of AcSIR courses.
  2. March 2019 – May 2019: Experienced researchervisit to Institute for Organic Chemistry, Technical University of Braunschweig, Germany, sponsored by Alexander von Humboldtfoundation.
    The research at TU Braunschweig was focused on the development of synthetic routes towards privileged heterocyclic scaffolds.
  3. March 2016 – to February 2019: Scientist Fellow(QHS) and Assistant Professor of AcSIR at Organic Chemistry Section, CSIR-NIIST, Thiruvananthapuram, India.
    The responsibilities at CSIR-NIIST include scientific research, mentoring of Doctoral and Masters’ students and teaching of AcSIR courses.
  4. October 2017 – November 2017: Experienced researchervisit to Institute for Organic Chemistry, Technical University of Braunschweig, Germany, sponsored by Alexander von Humboldtfoundation.
    The research at TU Braunschweig was focused on the development of synthetic routes towards privileged heterocyclic scaffolds.
  5. July 2015 – February 2016: DST-Young Scientistat Organic Chemistry Section, CSIR-NIIST, Thiruvananthapuram, India.
    The research at CSIR-NIIST was focused on the development of tandem transformations towards fused heterocycles.
  6. February 2013 – February 2015: Postdoctoral Fellowat University of Leuven (KU Leuven), Belgium. Research supervisors Prof. Dr. Jan Balzarini (Virologist) and Prof. Dr. Wim Dehaen (Organic Chemist).
    The research at KU Leuven mainly focused on the synthesis and biological testing (for its anti-viral properties) of novel phosphonucleosides. The initial results in this line were promising and found that the lead compound showed good activity against herpetic DNA polymerases. In addition, several other synthetic organic chemistry projects for the synthesis of functionalized heterocycles were undertaken.
  7. June 2011 - January 2013: Alexander von Humboldt Fellow at Institute for Organic Chemistry, Technical University of Braunschweig, Germany, in the group of Prof. Dr. Henning Hopf.
    The studies at Technical University of Braunschweig were mainly centered on the development of catalytic tandem reactions towards the synthesis of different heterocycles and carbocycles. Our investigations resulted in introducing a palladium catalyzed domino reaction towards substituted furanones.
  8. May 2010 - May 2011: CEA-Eurotalents Fellowat Centre for Atomic energy (CEA), Saclay, France, in the group of Dr. Eric Doris.
    The time spend at CEA under the guidance of Dr. Doris gave me the opportunity to get trained in the field of carbon nanotube-metal nanoparticle hybrid catalysis. The fabrication of the hybrid involved layer-by-layer (LBL) assembly of gold nanoparticles on carbon nanotubes. We could develop the first nanotube-based hybrid system for the oxidation of silanes.
  9. September 2005 - March 2010: Research Fellowat CSIR-NIIST, in the group of Dr. K. V. Radhakrishnan.
    Specialization in Synthetic Organic Chemistry: The topic doctoral thesis deals with palladium catalyzed transformations of azabicyclic olefins towards different substituted cyclopentenes.
  • CSIR Technology Award-2021(Certificate of Merit)
  • Drug Discovery Hackathon-2020 – Entry to 2nd Phase with Cash award and research funding.
  • Alexander von Humboldt(AvH) Experienced Researcher, Germany – 2017, 2019.
  • Academy of Scientific and Innovative Research (AcSIR), Assistant Professorship in the Faculty of Chemical Sciences – 2016.
  • Department of Science and Technology (DST), Start-up Research Grant(Young Scientists) – 2014.
  • Katholieke University of Leuven, Belgium, Incoming Postdoctoral Fellowship – 2013.
  • Alexander von Humboldt (AvH) Fellowship, Germany – 2011.
  • CEA-Eurotalents Fellowship (Marie Curie COFUND), France – 2010.
  • Junior Research Fellowship (JRF) and National Eligibility Test (NET), Council of Scientific and Industrial Research (CSIR) – 2005.
  • Graduate Aptitude Test in Engineering(GATE score: 90) – 2005.
  • 3rd rank from M. G. University, M.Sc. Chemistry – 2004.
  • Current h-index is 22 (Courtesy: Thomson Reuters).
  • Ph. D. in Chemistry (September 2005 – March 2010): Research Fellow at Organic Chemistry Section of CSIR-NIIST, Trivandrum, India, under the supervision of Dr. K. V. Radhakrishnan
  • M. Sc. in General Chemistry (3rd rank) (2002-2004) from St. Berchmans College, Changanacherry affiliated to Mahatma Gandhi University, India
  • B. Sc. in Chemistry (Main) with physics and mathematics as subsidiary subjects (1999-2002) from Christian College, Chengannur affiliated to University of Kerala, India
  • Ph. D. in Chemistry (September 2005 – March 2010): Research Fellow at Organic Chemistry Section of CSIR-NIIST, Trivandrum, India, under the supervision of Dr. K. V. Radhakrishnan
  • M. Sc. in General Chemistry (3rd rank) (2002-2004) from St. Berchmans College, Changanacherry affiliated to Mahatma Gandhi University, India
  • B. Sc. in Chemistry (Main) with physics and mathematics as subsidiary subjects (1999-2002) from Christian College, Chengannur affiliated to University of Kerala, India

Students

Vishnu

 

Dr. Vishnu K. Omanakuttan
Designation : Project Associate
Sheba

 

Miss Sheba Ann Babu
Designation : CSIR – Junior Research Fellow
Rahul

 

Mr. Rahul P.
Designation : CSIR – Junior Research Fellow
Anjana

 

Miss Anjana Siddharthan
Designation :Project Associate
Reshma

 

Mrs Reshma Elizabeth Lukose
Designation : Project Associate

 

Patents

  1. A PROCESS FOR THE SYNTHESIS OF BCX-1777 AND BCX-4430’
    Lankalapalli Ravi Shankar, Karunakaran Anitha Krishnakumar, Suresh Sanjay Varma, Velickakathu Omanakuttan Yadhukrishnan, Kapiya Sangeeth, Chekrain Valappil Shihas Ahammed, Bernard Prabha, Thangarasu Arun Kumar, Doddramappa Doddamani Shridevi, Jubi John, Kokkuvayil Vasu Radhakrishnan, Ayyappanpillai Ajayaghosh
    Indian Patent Application No. 202111061664 (Date of filing: 29/12/2021)
  2. ‘A short and cost effective synthetic route towards antiviral EIDD-1931 and its hydrate polymorphs’
    Jubi John, Sunil Varughese, K. V. Radhakrishnan, A. Ajayaghosh, Jagadeesh K., Divya I. S., Abhijith B., Akhil K. R., Priya S.
    Indian Patent Application No: 202111047808 (Dated: 20/10/2021)
  3. ‘A short and cost effective synthetic route towards antiviral drug Molnupiravir (EIDD-2801) from D-ribose’
    Jubi John, K. V. Radhakrishnan, Ravi Shankar L., Shridevi D., Sharathna P., Nitha P. R., A. Ajayaghosh

Publications

2023

  • ‘Graphitic Carbon Nitride (g-C3N4) Based Heterogenous Single Atom Catalysts: Synthesis, Characterisation and Catalytic Applications’
    Suja P., Jubi John, T. P. D. Rajan, Anilkumar M. Gopinathan, Takeo Yamaguchi, Suresh C. Pillai, Hareesh Unnikrishnan Nair Saraswathy
    J. Mater. Chem. A, 2023, DOI: 10.1039/D2TA09776A
  • ‘Dehydration-Driven Nanomechanical Responses of the Antiviral Drug EIDD-1931’
    Indira S. Divya, Amit Mondal, Surojit Bhunia, Kiran S. R. N. Mangalampalli, Jubi John, C. Malla Reddy*, Sunil Varughese*
    Cryst. Growth Des. 2023, DOI: 10.1021/acs.cgd.2c01445
  • ‘Palladium Catalyzed Ring-Opening of Diazabicylic Olefins with 4-Halo-1,3-dicarbonyl compounds: Accessing 3(2H)-Furanone Appended Cyclopentenes’
    Vishnu K. Omanakuttan, Alisha Valsan, Henning Hopf*, Jubi John*
    Organics, 2023, 4, 70–85
  • ‘Advances in the Synthesis of Fused 1,2,3-Triazoles via a MCR-Intramolecular Azide-Alkyne Cycloaddition Approach’
    Rahul P., Joice Thomas, Wim Dehaen, Jubi John*
    Molecules, 2023, 28, 308

2022

  • ‘Inverse Electron Demand Diels Alder Reaction of Aza-o-Quinone Methides and Enaminones: Accessing 3-Aroyl Quinolines and Indeno[1,2-b]quinolinones’
    Rahul P., Veena S., Jubi John*
    J. Org. Chem., 2022, 87, 13708–13714.
  • ‘An Efficient Magnesium Phyllosilicate-Nano Palladium Hybrid Catalyst for the Selective Oxidation of Organosilanes’
    P. V. Santhini, Gourab Das, Julie Mole,Abhijith S. Kumar, Balaraman Vedhanarayanan, Vakayil K. Praveen, Jubi John*
    ChemistrySelect, 2022, 7, e202200548.
  • ‘Tandem Reaction of 4-Halo-1,3-Dicarbonyl Compounds with Alkynes towards 4-Vinyl-3(2H)-Furanones and 3(2H)-Furanone fused 2-Pyridones’
    Vishnu K. Omanakuttan, P. V. Santhini, S. Shaludheen, Sunil Varughese, Henning Hopf, Jubi John*
    Asian J. Org. Chem., 2022, 11, e202200410.
  • ‘Base-Mediated Annulation of Electrophilic Benzothiophene with Naphthols and Phenols: Accessing Benzothiophene-Fused Heteroacenes’
    Akhil Krishnan R., Sheba Ann Babu, Nitha P. Ravi, Sreeja Thulasi, Jubi John*
    J. Org. Chem., 2022, 87, 8017–8027.
  • ‘Recent Advances towards the Synthesis and Material Applications of Indoloindoles’
    Dipankar Paul, Jubi John*
    Chem. Asian. J., 2022, 17, e202200460.

2021

  • ‘Indole Fused Heterocycles as Sensitizers in Dye-Sensitized Solar Cells: An Overview’
    P. R. Nitha, Suraj Soman*, Jubi John*
    Mater. Adv., 2021, 2, 6136-6168.
  • ‘Synthesis of Benzothienobenzofurans via Annulation of Electrophilic Benzothiophenes with Phenols’
    Akhil R Krishnan, Sheba Ann Babu, Nitha P. R., Jagadeesh Krishnan, Jubi John*
    Org. Lett. 2021, 23, 1814–1819.
  • ‘Unprecedented Access of Functionalized Pyrrolo[2,1-a]isoquinolines from the Domino Reaction of Isoquinolinium Ylides and Electrophilic Benzannulated Heterocycles’
    Sheba Ann Babu, Rajalekshmi A. R., Nitha P. R., Vishnu K. Omanakuttan, Rahul P., Sunil Varughese*, Jubi John*
    Org. Biomol. Chem. 2021, 19, 1807-1817.
  • ‘Synthesis of 3(2H)-Furanones: A Review’
    Vishnu K. Omanakuttan, Jubi John*, Henning Hopf*
    Eur. J. Org. Chem. 2021, 163-201.

2020

  • ‘Diazanorbornene: A Valuable Synthon towards Carbocycles and Heterocycles’
    Preethanuj Preethalayam, E. Jijy, Praveen Prakash, Sarath Chand Sarngadharan, Ajesh Vijayan, K. V. Radhakrishnan, Jubi John*
    Eur. J. Org. Chem. 2020, 6588-6613.
  • ‘Regulating Back Electron Transfer through Donor and π‐Spacer Alterations in Benzothieno[3,2‐b]indole‐based Dye‐sensitized Solar Cells’
    P. R Nitha, V. Jayadev, Sourava C. Pradhan, Velayudhan V. Divya, Cherumuttathu H. Suresh, Jubi John*, Suraj Soman*, Ayyappanpillai Ajayaghosh*
    Chem. Asian J. 2020, 15, 3503-3512.
  • ‘Superbase-Mediated Indirect Friedländer Reaction: A Transition Metal-Free Oxidative Annulation toward Functionalized Quinolines’
    Rahul P., Nitha P. R., Vishnu K. Omanakuttan, Sheba Ann Babu, P. Sasikumar, Vakayil K. Praveen, * Henning Hopf,* and Jubi John*
    Eur. J. Org. Chem. 2020, 3081–3089.

2019

  • ‘Tandem α-Arylation/Cyclization of 4-Haloacetoacetates with Arynes: A Metal-Free Approach towards 4-Aryl-3-(2H)-Furanones’
    Jubi John*, Vishnu K. Omanakuttan, Aneeja T., Cherumuttathu H Suresh, Peter G. Jones, Henning Hopf*
    J. Org. Chem. 2019, 84, 5957-5964.
  • ‘Absorption versus Recombination: Investigating the role of π-spacers in Indolo[3,2-b]indole based Dye Solar Cells’
    P. V. Santhini, V. Jayadev, Sourava C. Pradhan, Sivasankaran Lingamoorthy, Nitha P. R., Chaithanya M. V., Rakesh K. Mishra, Narayanan Unni K. N,* Jubi John*, Suraj Soman*
    New J. Chem. 2019, 43, 862-873.
  • ‘Alpha-carboxynucleoside phosphonates (α-CNPs): direct-acting inhibitors of viral DNA polymerases’
    Jan Balzarini, Alan Ford, N.M. Maguire, Jubi John, Kalyan Das, Eddy Arnold, Wim Dehaen, Anita Maguire
    Fut. Med. Chem. 2019 (DOI: 10.4155/fmc-2018-0324).

2018

  • ‘Accessing Highly Functionalized Cyclopentanoids via Cascade Palladation Approach: Unprecedented Benzylic C-H Activation towards Cyclopentenoindanes’
    P. V. Santhini, A. S. Smrithy, C. P. Irfana, S. Varughese, Jubi John*, K. V., Radhakrishnan*
    Chem. Commun. 2018, 54, 2982-2985.
  • ‘Sequential Ugi reaction/base induced ring closing/IAAC protocol toward triazolobenzodiazepine fused diketopiperazines and hydantoins’
    Robby Vroemans, Fante Bamba,Jonas Winters, Joice Thomas,Jeroen Jacobs, Luc Van Meervelt, Jubi John*, Wim Dehaen*
    Beilstein. J. Org. Chem. 2018, 14, 626-633.
  • ‘Lewis-Acid-Catalyzed Activation of Zerumbone towards Sesquiterpenoid Derivatives: Sustainable Utilization of Abundant Natural Resources for the Synthesis of Chemically Diverse Architectures’
    B. P. Dhanya, G. Gopalan, P. Sasikumar, S. Neethu, M. T. Meenu, P. Sharathna, Jubi John*, S. Varughese, M. Sabu, M. Dan, K. V. Radhakrishnan*
    Asian J. Org. Chem. 2018, 7, 471-476.

2017

  • ‘One-Pot MCR-Oxidation Approach toward Indole-Fused Heteroacenes’
    P. V. Santhini, A. S. Smrithy, C. P. Irfana, S. Varughese, Jubi John*, K. V., Radhakrishnan*
    J. Org. Chem. 2017, 82, 10537–10548.
  • ‘Heteroannulation of 3-Nitroindoles and 3-Nitrobenzo[b]thiophenes: A Multicomponent Approach toward Pyrrole-Fused Heterocycles’
    P. V. Santhini, Sheba Ann Babu, Akhil R. Krishnan, E. Suresh, Jubi John*
    Org. Lett. 2017, 19, 2458-2461.
  • ‘Direct Reductive Amination of Aldehydes via Environmentally Benign Bentonite-Gold Nanohybrid Catalysis’
    R. J. Maya, Susanna Poulose, Jubi John, R. Luxmi Varma*
    Adv. Synth. & Catal. 2017, 1177-1184.
  • ‘Lewis Acid Catalyzed Three-Component [3+2] Cycloaddition Reaction Using Pentafulvene as 2π Component: An Easy Way to Construct Pentaleno(1,2-b)indoles’
    P. V. Santhini, S. Sarath Chand, Jubi John; R. Luxmi Varma, Florian Jaroschik, K. V. Radhakrishnan*
    Synlett 2017, 28, 951-956.
  • ‘Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish’
    Yifan Zhang , Michiel Vanmeert, Aleksandra Siekierska, Annelii Ny, Jubi John, Geert Callewaert, Eveline Lescrinier, Wim Dehaen, Peter A. M. de Witte*, Rafal M. Kaminski*
    Sci. Rep. 2017, 7, 7195.
  • ‘Sequential Tandem Transformations of Functionalized Diazanorbornenes: Facile Strategy towards Pentacyclic Frameworks with Multiple Stereocenters’
    P. Preethanuj, V. Jijitha, Ajesh Vijayan, Jubi John; K. V. Radhakrishnan*
    Synthesis 2017, 49, 1816-1833.
  • ‘Pd-Catalyzed oxidative annulation of enamides with diazabicyclic olefins: rapid access to cyclopentene fused 2-pyrrolines’
    P. V. Santhini, G. Nimisha, Jubi John*, E. Suresh, R. Luxmi Varma, K. V. Radhakrishnan*
    Chem. Commun. 2017, 53, 1848-1851.

2016

  • ‘A bentonite-gold nanohybrid as a heterogeneous green catalyst for selective oxidation of silanes’
    R. J. Maya, Jubi John*, R. Luxmi Varma*
    Chem. Commun. 2016, 52, 10625-10628.
  • ‘Lewis Acid Catalysed Unprecedented Regioselective Hydroheteroarylation of Pentafulvenes’
    S. Sarath Chand, Greeshma Gopalan, P. V. Santhini, P. Preethanuj, Jubi John, Dominique Harakat, Jean-Luc Vasse, Florian Jaroschik, K. V. Radhakrishnan*
    Org. Lett. 2016, 18, 964-967.
  • ‘A General Metal-Free Route Towards the Synthesis of 1,2,3-Triazoles from Readily Available Primary Amines and Ketones’
    Joice Thomas, Sampad Jana, Jubi John, Wim Dehaen*
    Chem. Commun. 2016, 52, 2885-2888. (Cover Page)

2015

  • ‘Pronounced Inhibition Shift from HIV Reverse Transcriptase to Herpetic DNA Polymerases by Increasing the Flexibility of α‑Carboxy Nucleoside Phosphonates’
    Jubi John, Youngju Kim, Nicholas Bennett, Kalyan Das, Sandra Liekens, Lieve Naesens, Eddy Arnold, Anita R. Maguire, Mathias Götte, Wim Dehaen*, Jan Balzarini*
    J. Med. Chem. 2015, 58, 8110-8127.
  • ‘Organocatalytic Routes toward Substituted 1,2,3-Triazoles’
    Jubi John, Joice Thomas, Wim Dehaen*
    Chem. Commun. 2015, 51, 10797-10806.
  • ‘Tandem Organocatalyzed Knoevenagel Condensation/1,3-Dipolar Cycloaddition towards Highly Functionalized Fused 1,2,3-Triazoles’
    Jubi John, Joice Thomas, Nikita Parekh, Wim Dehaen*
    Eur. J. Org. Chem. 2015, 4922-4930.
  • ‘Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics’
    Jan Balzarini*, Kalyan Das, Jean A. Bernatchez, Sergio Martinez, Sarah Keane, Alan Ford, Nuala Maguire, Niki Mullins, Jubi John, Youngju Kim, Wim Dehaen, Johan Vande Voorde, Sandra Liekens, Lieve Naesens, Matthias Götte, Anita R. Maguire, Eddy Arnold.
    Proc. Natl. Acad. Sci. U.S.A. 2015, 112, 3475-3480.

2014

  • ‘A Metal-Free Three-Component Reaction for the Regioselective Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles’
    Joice Thomas, Jubi John, Nikita Parekh, Wim Dehaen*
    Angew. Chem. Int. Ed. 2014, 53, 10155-10159.
  • ‘Size effect of gold nanoparticles supported on carbon nanotube as catalysts in selected organic reactions’
    Dhanaji Jawale, Edmond Gravel, Valérie Geersten, Haiyan Li, Nimesh Shah, Rahul Kumar, Jubi John, Irishi Namboothiri*, Eric Doris*
    Tetrahedron 2014, 70, 6140-6145.
  • ‘Synthetic Protocol toward Fused Pyrazolone Derivatives via a Michael Addition and Reductive Ring Closing Strategy’
    Nikita Parekh, Joice Thomas, Jubi John, Radhika Kusurkar, Wim De Borggraeve, Wim Dehaen*
    J. Org. Chem. 2014, 79, 5338-5344.
  • ‘Tandem Mannich Addition-Palladium Catalyzed Ring Closing Strategy toward 4-Substituted 3(2H)-Furanones’
    Jubi John, Eliza Târcoveanu, Peter G. Jones, Henning Hopf*
    Beilstein. J. Org. Chem. 2014, 10, 1462-1470.

2013

  • ‘An Efficient and Exclusive Approach to 3,4-Disubstituted Cyclopentenes via Palladium Catalyzed Ring Opening of Azabicyclic olefins with Aryl halides’
    Nayana Joseph, Rani Rajan, Jubi John, Devika N. V., Sarath Chand S., E. Suresh, Petri Pihko, K. V. Radhakrishnan*
    RSC Advances 2013, 3, 7751-7757.
  • ‘Palladium Catalyzed Reaction of Bicentered Nucleophiles with Bicyclic Hydrazines: Facile Route towards Heteroannulated Cyclopentenes and Azabicycles’
    Jubi John, Rani Rajan, S. Sarath Chand, Praveen Prakash, Nayana Joseph, Eringathodi Suresh, K. V. Radhakrishnan*
    Tetrahedron 2013, 69, 152-159.
  • ‘Palladium Catalyzed Tandem Michael Addition-Ring Closing Protocol towards Substituted 3(2H)-furanones’
    Jubi John, Henning Hopf*
    Eur. J. Org. Chem. 2013, 841-845.

2012

  • ‘Advances in carbon nanotube-noble metal catalyzed organic transformations’
    Jubi John, Edmond Gravel, Irishi N. N. Namboothiri*, Eric Doris*
    Nanotechnol. Rev. 2012, 515-539.

2011

  • ‘Catalytic Oxidation of Silanes by Carbon Nanotube-Gold Nanohybrids’
    Jubi John, Edmond Gravel, Agnes Hagege, Haiyan Li, Thierry Gacoin, Eric Doris*
    Angew. Chem. Int. Ed. 2011, 50, 7533-7536.
  • ‘Tumor-Targeted Polydiacetylene Micelles for In Vivo Imaging and Drug Delivery’
    Nicolas Mackiewicz, Edmond Gravel, Anikitos Garofalakis, Julien Ogier, Jubi John, Daniel Miotto Dupont, Karine Gombert, Bertrand Tavitian, Eric Doris*, Frédéric Ducongé*
    Small 2011, 7, 2786-2792.
  • ‘Transition metal catalyzed carboannulation of diazabicyclic alkenes with ambiphilic bifunctional reagents: a facile route towards functionalized indanones and indanols’
    Nayana Joseph, Jubi John, Rani Rajan, Sreeja Thulasi, Anupa Mohan, E. Suresh, K. V. Radhakrishnan*
    Tetrahedron 2011, 67, 4905.

2010

  • ‘Palladium-Catalyzed Bis-Functionalization of Isatylidenes: A Facile Route towards Spiro-Indol-2-ones’
    Sholly Clair George, Jubi John, S. Anas, Joshni John, Yoshinori Yamamoto, E. Suresh, K. V. Radhakrishnan*
    Eur. J. Org. Chem. 2010, 5489.
  • ‘Trapping the -Allylpalladium Intermediate from Fulvene-Derived Azabicyclic Olefin with Soft Nucleophiles’
    Rani Rajan, Jubi John, Sreeja Thulasi, Nayana Joseph, K. V. Radhakrishnan*, R. C. Sawant
    Synthesis 2010, 3649.
  • ‘Palladium-Catalyzed Ring Opening of Azabicyclic Olefins with Organoindium and Gallium Reagents: A Facile Access Towards Benzylated Cyclopentanoids’
    Jubi John, B. Adarsh, K.V. Radhakrishnan*
    Tetrahedron 2010, 66, 1383.

2009

  • ‘Desymmetrization of Meso Bicyclic Hydrazines: An Efficient Strategy towards the Synthesis of Functionalized Cyclopentenes’
    V. S. Sajisha, S. Anas, Jubi John, K. V. Radhakrishnan*
    Synlett 2009, 2885.
  • ‘Palladium Catalyzed Tandem Ring Opening-Ring Closing Reaction of Diazabicyclic Alkenes: A Facile One Pot Strategy for Cyclopentannulation of Heterocycles’
    Jubi John, Indu U., Eringathodi Suresh and K. V. Radhakrishnan*
    J. Am. Chem. Soc. 2009, 131, 5042.

2008

  • ‘Stereo controlled Synthesis of Novel Spirocyclic Oxabridged Cyclooctanoids through Sequential Transformations of Pentafulvenes’
    K. S. Krishnan, J. M. Kuthanappillil, Jubi John, E. Suresh, K. V. Radhakrishnan*
    Synthesis 2008, 2134.
  • ‘Facile synthesis of substituted alkylidene cyclopentenes via palladium catalyzed ring opening of fulvene derived bicyclichydrazines’
    S. Anas, V. S. Sajisha, Jubi John, N. Joseph, S. C. George, K. V. Radhakrishnan*
    Tetrahedron 2008, 64, 9689.

2007

  • ‘Iodine assisted Palladium Catalyzed Ring opening of Bicyclic Hydrazines with Organoboronic acids: Stereoselective Synthesis of Functionalized Cyclopentenes/Alkylidene Cyclopentenes’
    S. Anas, Jubi John, V. S. Sajisha, Joshni John, Rani Rajan, E. Suresh, K. V. Radhakrishnan*
    Org. Biomol. Chem. 2007, 5, 4010.
  • ‘Palladium Catalyzed Ring Opening of Azabicyclic Olefins with Organoindium Reagents: A Simple, Clean and Efficient Synthesis of Functionalized Cyclopentenes’
    Jubi John, S. Anas, V. S. Sajisha, S. Viji, K. V. Radhakrishnan*
    Tetrahedron Lett. 2007, 48, 7225.

2006

  • ‘Iodine Assisted Modified Suzuki Type Reaction of Bicyclic Hydrazines: Stereoselective Synthesis of Functionalized Cyclopentenes’
    Jubi John, V. S. Sajisha, S. Mohanlal, K. V. Radhakrishnan*
    Chem. Commun. 2006, 3510.

Dr. John’s research is mainly focused on the synthesis of organic motifs for medicinal and material applications. The group is currently focusing on the development of anti-viral drug candidates targeting both DNA and RNA viruses. In addition, exploration of novel homogeneous and heterogeneous catalyzed organic reactions and devising new reactions towards fused heterocycles are being pursued.